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With Regards To MHC lessons We antigen presentation, cTECs show exclusive catalytic subunit for the proteasome described as I?5t Proteasomes that include I?5t are described as a€?thymoproteasomesa€™. Obtained a substrate desires that's unique from proteasomes containing the I?5 or I?5i subunits 4 (termed a€?housekeeping proteasomesa€™ and a€?immunoproteasomesa€™, correspondingly). Rats missing thymoproteasomes program a substantial defect...